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Nucleic Acids Research, 2001, Vol. 29, No. 1 291-293
© 2001 Oxford University Press

The Homeodomain Resource: sequences, structures, DNA binding sites and genomic information

Sharmila Banerjee-Basu, Daniel W. Sink and Andreas D. Baxevanis*

Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

The Homeodomain Resource is an annotated collection of non-redundant protein sequences, three-dimensional structures and genomic information for the homeodomain protein family. Release 3.0 contains 795 full-length homeodomain-containing sequences, 32 experimentally-derived structures and 143 homeo­box loci implicated in human genetic disorders. Entries are fully hyperlinked to facilitate easy retrieval of the original records from source databases. A simple search engine with a graphical user interface is provided to query the component databases and assemble customized data sets. A new feature for this release is the addition of DNA recognition sites for all human homeodomain proteins described in the literature. The Homeodomain Resource is freely available through the World Wide Web at http://genome.nhgri.nih.gov/homeodomain.

* To whom correspondence should be addressed. Tel: +1 301 496 8570; Fax: +1 301 402 6858; Email: andy{at}nhgri.nih.gov


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