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Nucleic Acids Research, 2004, Vol. 32, Database issue D572-D574
© 2004 Oxford University Press

Hembase: browser and genome portal for hematology and erythroid biology

Sung-Ho Goh, Y. Terry Lee, Gerard G. Bouffard1 and Jeffery L. Miller*

Laboratory of Chemical Biology, National Institute of Diabetes and Digestive and Kidney Diseases and 1 National Human Genome Research Institute, National Institutes of Health, 9000 Rockville Pike, MD 20892, USA

*To whom correspondence should be addressed. Tel: +1 301 480 1908; Fax: +1 301 435 5148; Email: jm7f{at}nih.gov

Hembase (http://hembase.niddk.nih.gov) is an integrated browser and genome portal designed for web-based examination of the human erythroid transcriptome. To date, Hembase contains 15 752 entries from erythroblast Expressed Sequenced Tags (ESTs) and 380 referenced genes relevant for erythropoiesis. The database is organized to provide a cytogenetic band position, a unique name as well as a concise annotation for each entry. Search queries may be performed by name, keyword or cytogenetic location. Search results are linked to primary sequence data and three major human genome browsers for access to information considered current at the time of each search. Hembase provides interested scientists and clinical hematologists with a genome-based approach toward the study of erythroid biology.


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