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Nucleic Acids Research 2005 33(Database Issue):D212-D215; doi:10.1093/nar/gki034
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Nucleic Acids Research, 2005, Vol. 33, Database issue D212-D215
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved

The ProDom database of protein domain families: more emphasis on 3D

Catherine Bru, Emmanuel Courcelle, Sébastien Carrère, Yoann Beausse, Sandrine Dalmar and Daniel Kahn*

Laboratoire des Interactions Plantes-Microorganismes, INRA/CNRS, BP 27, F-31326 Castanet-Tolosan Cedex, France

* To whom correspondence should be addressed. Tel: +33 5 61 28 53 29; Fax: +33 5 61 28 50 61; Email: Daniel.Kahn{at}toulouse.inra.fr

Received September 15, 2004; Revised and Accepted September 23, 2004

ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (3D) information from the SCOP database; a completely redesigned web interface (http://www.toulouse.inra.fr/prodom.html); visualization of ProDom domains on 3D structures; coupling of ProDom analysis with the Geno3D homology modelling server; Bayesian inference of evolutionary scenarios for ProDom families. In addition, we have developed ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics.

The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use permissions, please contact journals.permissions{at}oupjournals.org.


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