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Nucleic Acids Research Advance Access originally published online on November 6, 2006
Nucleic Acids Research 2007 35(Database issue):D141-D144; doi:10.1093/nar/gkl815
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Nucleic Acids Research, 2007, Vol. 35, Database issue D141-D144
© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Articles

dbRES: a web-oriented database for annotated RNA editing sites

Tao He, Pufeng Du and Yanda Li*

Bioinformatics Division, TNLIST and Department of Automation Tsinghua University, Beijing 100084, China

*To whom correspondence should be addressed: Tel: +86 10 62794295; Fax: +86 10 62794295; Email: daulyd{at}tsinghua.edu.cn

Received August 7, 2006. Revised October 3, 2006. Accepted October 4, 2006.

Although a large amount of experimentally derived information about RNA editing sites currently exists, this information has remained scattered in a variety of sources and in diverse data formats. Availability of standard collections for high-quality experimental data will be by of great help for systematic studying of RNA editing, especially for developing computational algorithm to predict RNA editing site. dbRES (http://bioinfo.au.tsinghua.edu.cn/dbRES) is a public database of known RNA editing sites. All sites are manually curated from literature and GenBank annotations. dbRES version 1.1 contains 5437 RNA editing sites of 251 transcripts, covering 96 organisms across plant, metazoan, protozoa, fungi and virus. dbRES provides comprehensive annotations and data summaries, including (but not limited to) transcript sequences, RNA editing types, editing site locations, amino acid changes, organisms, subcellular organelles (if available), cited references, etc. A user-friendly web interface is developed to facilitate both retrieving data and online display of RNA edit site information.

The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors


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